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. 2013 Jul;98(7):2645–2655. doi: 10.1210/jc.2013-1440

Table 6.

Controversies and Areas of Uncertainty

Optimal glucocorticoid replacement regimens
    Hydrocortisone dosing, controlled-release preparations, sc pump
    Other glucocorticoids
Use of antiandrogens and androgen biosynthesis inhibitors
Goals for optimal laboratory parameters
    Incorporation of steroid profiling by mass spectrometry
Initial assessment of young men with 21OHD, including sperm banking
Management recommendations during menopausal transition
Indications for additional surgeries