Table 1.

Clinical Characteristics of Adolescent Boys with AN and Normal-Weight Controls^a

	AN	Controls	P Value
n	15	16
Age, y	16.01 ± 1.96	15.66 ± 1.86	NS
Bone age, y	16.18 ± 1.57	16.17 ± 2.28	NS
Bone age/chronological age	1.02 ± 0.11	1.03 ± 0.06	NS
Age at diagnosis of anorexia nervosa, y	15.2 ± 1.8
Duration since diagnosis, months	9.3 ± 14.2
Testicular size, mL	10.5 ± 6.1	18.7 ± 5.9	.002
Tanner stage for pubic hair	4.0 ± 1.5	4.5 ± 0.8	NS
Weight, kg	50.66 ± 9.81	61.99 ± 9.31	.002
Weight SDS	−1.02 ± 0.20	0.13 ± 0.19	.0002
Height, cm	170.23 ± 10.39	170.56 ± 7.25	NS
Height SDS	−0.14 ± 1.14	0.14 ± 1.25	NS
BMI, kg/m2	17.27 ± 1.69	21.27 ± 2.71	<.0001
BMI SDS	−1.16 ± 0.42	0.09 ± 0.76	<.0001
Fat mass, kg	6.95 ± 2.30	9.98 ± 3.49	.008
Lean body mass, kg	43.65 ± 8.48	51.27 ± 7.83	.01
Percent body fat	13.2 ± 3.6	15.6 ± 4.1	.09
Hip BMD, g/cm3	0.86 ± 0.14	1.0 ± 0.13	.006
Hip BMD Z-score	−1.11 ± 1.00	0.03 ± 0.75	.001
Hip BMD Z-score < −1, %	53.3	18.8	.05
Femoral Neck BMD, g/cm3	0.78 ± 0.11	0.90 ± 0.13	.01
Femoral Neck BMD Z-score	−1.11 ± 0.84	−0.12 ± 0.86	.003
Femoral neck BMD Z-score <−1, %	60.0	12.5	.009
Trochanteric BMD, g/cm3	0.67 ± 0.11	0.79 ± 0.07	.0007
Trochanteric BMD Z-score	−1.15 ± 0.83	−0.02 ± 0.60	.0001
Trochanteric BMD Z-score <−1, %	66.7	0	<.0001
Intertrochanteric BMD, g/cm3	0.98 ± 0.17	1.15 ± 0.17	.01
Intertrochanteric BMD Z-Score	−0.99 ± 1.17	0.16 ± 0.82	.003
Intertrochanteric BMD Z-score <−1, %	53.3	12.5	.02
Testosterone, ng/dL	172.5 ± 142.1	445.0 ± 201.2	.0005
Estradiol, pg/mL	11.6 ± 4.5	18.6 ± 7.2	.006
IGF-I, ng/mL	456.7 ± 264.6	567.5 ± 244.3	NS

Abbreviation: NS, not significant.

^aResults are shown as mean ± SD or percent. P values < .1 are shown, and significant P values are in bold.