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Genomic complexity of MDIRs. Genomic Southern blot hybridization using probes representing each of the four types of MDIR IgSF domain (I, MDIR1IgD1; II, MDIR2IgD1; III, MDIR2IgD2; IV, MDIR4IgD2). Samples were digested with either EcoRI (E) or HindIII (H)