Table 1.
Comparison of uni and SHAM ratios derived from gene array and by rtPCR signals
| Probe ID | Gene symbol | UNI array ratio | UNI rtPCR ratio | SHAM array ratio | SHAM rtPCR ratio |
|---|---|---|---|---|---|
| 1423954 | C3 | 10.29 | 11.37±2.91* | 3.71 | 2.29±0.31* |
| 1418126 | CCL5 | 5.51 | 8.12±4.01 | 2.89 | 1.16±0.27 |
| 1460227 | TIMP1 | 99 | 74.1±14.13** | –# | 4.63±1.94 |
| 1419089 | TIMP3 | 1.11 | 2.12±0.66 | 1.12 | 0.79±0.07 |
| 1417256 | MMP13 | 0.96 | 0.44±0.08** | 0.47 | 0.57±0.22* |
| 1448162 | VCAM1 | 4.66 | 7.61±2.13* | 0.74 | 0.64±0.07* |
| 1422142 | nephrin | 0.36 | 0.53** | 0.66 | 0.49* |
| 1423110 | collagen 1 | 6.48 | 10.83** | 1.35 | 1.875 |
| 1427884 | collagen 3 | 5.46 | 7.79* | 1.92 | 0.86 |
The UNI ratio was obtained by dividing OVE-uni by FVB-uni and the SHAM ratio was obtained by dividing OVE-sham by FVB-sham. For rtPCR, 4 samples were used per group. For gene array, the same 4 RNA samples were pooled to prepare one probe per group.
* p<0.05,
** p<0.01 for OVE versus FVB.
# Both OVE and FVB values were reported as absent on gene array.