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. 2013 Jul 4;8(7):e67926. doi: 10.1371/journal.pone.0067926

Table 4. The prediction of FGSG_06878 as a virulence factor with links to 8 seeds.

FGSG_06878 (probable CMK1 - Ca2+/calmodulin-dependent ser/thr protein kinase type I) is linked by Seeds on which the prediction is based with phenotype [], and MIPS annotation.Phenotype symbols are rv = reduced virulence, lp = loss of pathogenicity
Predicted PPI to: FGSG_09903 (ste7) [lp], Probable map kinase kinase FGSG_10313 [rv] (mgv1) (MGV1 map kinase) FGSG_06385 (map1) [lp] (FMK1 pathogenicity map kinase 1
Co-expression to: FGSG_08737 (GzOB031) [rv] Probable woronin body major protein precursor FGSG_01964 (CHS5) [rv] Probable chitin synthase FGSG_00385 (GzHMG002) [rv] probable NHP6B - nonhistone chromosomal protein
Sequence similarity to: FGSG_09897 (snf1) [rv] probable serine/threonine protein kinase FGSG_06385 (map1) [lp] (FMK1 pathogenicity map kinase 1) FGSG_16491 (fst11) [lp]] related to NRC-1 MAPKK kinase

This prediction FGSG_06878 was confirmed to be a virulence protein in the recent paper of [21-Wang et al.]. Note that prediction FGSG_06878 is linked to seed FGSG_06385 by both predicted PPI and sequence similarity information. In planta phenotypes are rv, reduced virulence, a quantitative reduction in disease causing ability and the more stringent lp, indicating loss of pathogenicity where disease establishment is aborted.