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. 2013 Jul 4;8(7):e67851. doi: 10.1371/journal.pone.0067851

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© 2013 Hu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Data summarizing STAT3 mutations in DLBCL tumors (n = 40) (B) Chromatograms of STAT3 DNA sequence showing 857T>A heterozygous mutation. (C) Modular structure of STAT3 showing that Methionine 206 is located in the coiled-coiled domain of STAT3. Alignment of part of STAT3 protein sequence from various species showing that methionine 206 is a conserved amino acid.