Figure 4. Tan IIA in combination with GCV causes greater growth inhibition on a mixture of HSV-tk and WT B16 cells.

HSV-tk B16 cells were mixed with WT B16 cell line at a ratio of 1∶9. The mixture of cells was left untreated or treated with Tan IIA (10 or 20 µM) for 24 h, and then was cultured with or without GCV (15.7 µM) for 48 h followed by MTT assay. *p<0.05, **p<0.01 compared with control; ^##p<0.01 compared with Tan IIA or GCV treatment alone.