Figure 3. Testing of spatial learning and memory in Dhal S and S.R2A congenic female rats.

(A) Acquisition performance measured as mean distance in cm during the 24 trials (•, Dahl S; ○, S.R2A). Percentage distance traveled in quadrants (B, C, D) and spatial accuracy performance (E) during the probe trial after completion of Morris water maze training. Quadrants are: target (T), opposite (O), adjacent right (A_R) and adjacent left (A_L). ^** P<0.01. Data represent means ± s.e.m. (one-way ANOVA followed by Holm-Sidak’s test for quadrant occupancy in the probe trial of the Morris water maze task and for spatial accuracy performance).