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. 2013 Jul 4;8(7):e68083. doi: 10.1371/journal.pone.0068083

Figure 1. Binding of Anti-EpoR antibodies to spleens from WT or human EpoR KI mice.

Figure 1

Spleens from untreated or rMsEpo-treated mice were sectioned and stained with anti-EpoR antibodies as described in Methods. Note the enlargement in spleen with rMsEpo addition due to enhanced erythropoiesis. (A) Staining with anti-EpoR monoclonal antibody A82. (B) The same sections as in A were stained with polyclonal antibody M-20. (C) Staining of mouse WT small intestine (ileum) with A82. Note the staining of the material in secretory granules and just under the surface. (D) A82 Western blot with mouse tissues. Note the ∼ 45 kDa protein non-EpoR protein in small intestine.