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. 2013 Jul 4;9(7):e1003606. doi: 10.1371/journal.pgen.1003606

Figure 5. The role of gypsy orientation and distance between gypsy insulators in blocking the eye enhancer.

Figure 5

The eye enhancer is inserted in the center of a 4.3-kb domain bordered by the gypsy insulators located (A) in the opposite or (B) in the same orientation. (C) Insertion of additional 2-kb DNA fragment between the 4.3-kb domain bordered by the gypsy insulators and the white promoter. (D, E) The eye enhancer is inserted in a 5.5-kb loop formed by the gypsy insulators located (D) in the opposite or (E) in the same orientation. Designations are as in Figures 1 and 4.