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. Author manuscript; available in PMC: 2013 Jul 4.
Published in final edited form as: Expert Rev Anticancer Ther. 2011 Aug;11(8):1283–1294. doi: 10.1586/era.11.111

Table 3.

Commonly used inhibitors of autophagy.

Compound Target and effect
Hydroxychloroquine or chloroquine Lysosomal pH, prevents autophagosome–lysosome fusion
3-methyladedine Class III PI3K inhibition, prevents autophagosom formation
Wormatin Class III PI3K inhibition, prevents autophagosome formation
LY294002 Class III PI3K inhibition, prevents autophagosome formation
Bafilomycin A1 Vacuolar ATPase inhibition, prevents autophagosome–lysosome fusion