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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Addict Biol. 2013 Mar 18;19(5):907–917. doi: 10.1111/adb.12051

Figure 3. Age by Session Interactions.

Figure 3

A) Significant session and age group interaction on BOLD signal change (MF/CG Wald χ2(1)=14.52, p=0.0001; left DLPFC Wald χ2(1)=16.08, p=0.0001; right DLPFC Wald χ2(1)=17.45, p<0.0001). BOLD signal was significantly reduced in all three a priori ROIs during the abstinent session for the <50 age group but not for those ≥50 yrs. (p values of 0.0001 for MF/CG and R DLPFC in the > 50 age group and p<0.001 for the L DLPFC; corresponding p values in the <50 age group: 0.90 for MF/CG, 0.44 for R DLPFC, and 0.58 for L DLPFC). B) Significant session by age interaction on withdrawal (Wald χ2(1)=7.31, p=0.007). Session effects were significant in both age groups (ps < 0.0001) but attenuated in the >50 age group. C) Significant session by age interaction on craving (Wald χ2(1)=7.02, p=0.008). Again, session effects were significant in both age groups (ps < 0.0001) but attenuated in the >50 age group.