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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Cancer Prev Res (Phila). 2013 May 16;6(7):675–685. doi: 10.1158/1940-6207.CAPR-13-0064

Figure 3. Effect of aspirin or NO-aspirin on UV-induced skin tumorigenesis.

Figure 3

Groups of 20 female SKH-1 mice were placed on their experimental diets and exposed to UV irradiation thrice weekly. Tumors were counted weekly and the data calculated as the average number of tumors per mouse (panel A). Tumor multiplicity for 60 ppm aspirin and 1350 ppm NO-aspirin were significantly (p<0.05) different from the UV control group; 750 ppm aspirin was very significantly (p<0.001) different from the UV control. Tumor incidence (panel B) was calculated as the percentage of mice bearing tumors. Although mice in the 1350 ppm aspirin group developed tumors more slowly than the other groups, this was not statistically different.