Table 4.
Breast cancer risk and recurrence rates among BRCA mutation carriers and individuals without BRCA mutations.
Type of patient | Probability of Breast Cancer over lifetime | Probability of contralateral breast cancer | Probability of synchronous contralateral breast cancer |
---|---|---|---|
BRCA mutation carriers | BRCA 1 mutation: 57-65% BRCA 2 mutation: 45-69% 140-143 |
40% within 10 years after initial diagnosis of breast cancer 140-143 | 3-5% 139,144 |
Individuals without BRCA mutation | 12.2% 145 | 6% within 10 years after initial diagnosis of breast cancer 146 | 3-5% 139,14 |