Table 1.

Mean values of relative protein levels of shelterin components in primary and hTERT-immortalized fibroblasts of LMNA mutant cell lines. Protein levels in mutant lines were normalized to the average in controls, 82-6 and 82-6 hTERT.

Shelterin components	LMNA mutant cell lines
	PORTU8010		NORWAY1010
	R133L	R133L hTERT	L140R	L140R hTERT
TRF2	0.462	0.544	0.453	0.370
TRF1	0.726	0.429	0.736	0.362
POT1	0.574	0.491	0.562	0.470
TIN2	0.363	0.785	0.345	0.590
hRap1	0.460	0.590	0.398	0.312
TPP1	0.623	1.319	0.921	1.212