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. 2013 Jul 5;4:166. doi: 10.3389/fphys.2013.00166

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Copyright © 2013 Adeniran, Hancox and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

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Simulation of ventricular action potentials and the time course of I_Kr and I_K1. (Ai–Ci) Steady state (at a stimulation frequency of 1 Hz) action potentials for EPI (Ai), MCELL (Bi), and ENDO (Ci) cells under wild-type (WT; black), SQT1 (blue) and SQT3 (green) conditions. (Aii–Cii) Corresponding I_Kr current profiles for EPI (Aii), MCELL (Bii), and ENDO (Cii) cells under the WT (black) and SQT1 (blue) conditions. (Aiii–Ciii) Corresponding I_K1 current profiles for EPI (Aiii), MCELL (Biii), and ENDO (Ciii) cells under the WT (black) and SQT1 (blue) conditions.