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. 2013 Jul 5;4:166. doi: 10.3389/fphys.2013.00166

Figure 3.

Figure 3

Single cell effects of the SQT1 and SQT3 mutations (without Isac). (Ai–Ci) WT (black), SQT1 (blue) and SQT3 (green) action potentials in the EPI (Ai), MCELL (Bi), and ENDO (Ci) cell models. (Aii–Cii) WT (black), SQT1 (blue) and SQT3 (green) intracellular calcium concentration and Ca2+ transients in the EPI (Aii), MCELL (Bii), and ENDO (Cii) cell models. (Aiii–Ciii) WT (black), SQT1 (blue) and SQT3 (green) sarcomere length (SL) in the EPI (Aiii), MCELL (Biii), and ENDO (Ciii) cell models. (Aiv–Civ) WT (black), SQT1 (blue) and SQT3 (green) active force in the EPI (Aiv), MCELL (Biv), and ENDO (Civ) cell models. Values are normalized to WT maximum active force for each cell type.