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. Author manuscript; available in PMC: 2014 Jul 2.
Published in final edited form as: Structure. 2013 Jul 2;21(7):1085–1096. doi: 10.1016/j.str.2013.05.009

Figure 8. AniAni interactions in GP2 post-fusion conformations.

Figure 8

EBOV GP2) The 6-helix bundle of ebola GP2 is depicted, the CHR is colored gold and the NHR is colored green (2EBO). Panel A shows the AniAni interaction found between the CHR and the NHR. In grey is an overlay of the neutral pH structure (1EBO) and the low pH structure (2EBO). MARV GP2) MARV GP2 post-fusion state is colored akin to EBOV GP2, with the GCN4 trimerization tag colored grey (4G2K). AniAni pairs that make up the anionic stripe can be seen in panels B and C.