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Bar chart with standard deviation showing a time and concentration-dependent effect on human fibroblast mitochondrial activity after 30- minute exposure to fentanyl. A significant difference in mitochondrial activity was detectable after 1 h, 24 h and 7 days in the 0.05% group and after 1 hour in the 0.025% group (*p < 0.05 vs. DMEM-only)
