Table 1.

Allele frequencies of SNPs in putative N-6 adenine-specific DNA methyl­transferase 1 (N6AMT1).

SNPb	SNP typeb	Basec	Positionb	n	Andean study population	HapMap allele frequenciesa (%)
					Allele frequency (%)d	European	Asian	African
rs1997605	Intron 1	A/G	30257418	188	53/47	85/15	50/50	65/35
rs2205449	Intron 4	A/T	30252088	188	38/63	59/41	25/75	18/82
rs2705671	Intron 4	T/G	30251349	184	58/42	86/14	69/31	94/6
rs16983411	Intron 5	A/G	30250247	185	99/1	84/16	87/13	82/18
rs1048546	3´UTR	G/T	30244877	187	53/47	69/31	37/63	59/41
aAllele frequencies for Europeans, Asians, and Africans from HapMap CEU (CEPH, Utah residents with ancestry from northern and western Europe), JPT (Japanese in Tokyo, Japan), and YRI (Yoruba in Ibadan, Nigeria), respectively (Thorisson etal. 2005). bFrom the NCBI dbSNP Single Nucleotide Polymorphisms database (http://www.ncbi.nlm.nih.gov/SNP), genome build 37.3. cAlleles associated with lower %MMA are denoted first. dChi-square values from the test of Hardy Weinberg equilibrium were 2.73 for rs1997605, 0.41 for rs2205449, 3.21 for rs2705671, <0.001 for rs16983411, and 2.11 for rs1048546.