. 2013 May 10;121(7):797–803. doi: 10.1289/ehp.1206003

Table 6.

N6AMT1 gene expression expressed as relative fluorescence units, stratified by N6AMT1 SNPs and haplotypes

N6AMT1 SNP or haplotype^a	Genotype or no. of copies	n	ILMN_2315569	ILMN_1754988
N6AMT1 SNP or haplotype^a	Genotype or no. of copies	n	Mean (95%CI)	Mean (95%CI)
rs1997605	AA	24	117.2 (111.3, 123.0)	111.0 (108.0, 114.0)
	AG	24	126.2 (119.8, 133.9)	114.7 (111.9, 117.8)
	GG	15	122.9 (112.6, 133.2)	115.2 (111.3, 119.1)
		p = 0.12^b	p = 0.10^b
rs2205449	AA	11	114.7 (107.3, 122.1)	113.9 (108.7,119.1)
	TA	24	120.3 (114.4, 126.3)	112.3 (109.9, 114.7)
	TT	28	126.3 (119.5, 134.2)	114.2 (111.1, 117.5)
		p = 0.09^b	p = 0.60^b
rs2705671	TT	28	116.8 (111.3, 120.7)	111.9 (108.9, 114.9)
	GT	24	127.3 (120.8, 135.1)	114.6 (111.7, 117.8)
	GG	11	119.6 (107.7, 131.6)	115.7 (111.8, 119.6)
		p = 0.047^b	p = 0.22^b
rs1048546	GG	21	115.6 (109.3, 121.8)	111.0 (107.5, 114.6)
	GT	28	126.1 (120.3, 132.9)	114.3 (111.8, 117.0)
	TT	14	122.7 (111.6, 133.8)	115.5 (111.3, 119.6)
		p = 0.073^b	p = 0.15^b
Haplotype1	2 copies	11	114.7 (107.3, 122.1)	113.9 (108.7, 119.1)
	1 copy	24	120.3 (114.4, 126.3)	112.3 (109.9, 114.7)
	0 copies	28	126.3 (119.5, 134.2)	114.2 (111.2, 117.5)
		p = 0.09^b	p = 0.60^b
Haplotype 3	1 and 2 copies	21	125.7 (117.6, 133.7)	111.8 (108.2, 115.4)
	0 copies	42	120.5 (115.6, 125.4)	114.3 (112.2, 116.4)
		p = 0.24^b	p = 0.20^b
Haplotype 9	0 copies	27	117.2 (111.9, 121.5)	111.7 (108.8, 114.7)
	1 copy	26	128.1 (121.9, 135.5)	114.1 (111.3, 117.2)
	2 copies	10	119.1 (105.7, 132.4)	116.1 (118.9, 120.4)
		p = 0.029^b	p = 0.20^b
^aThe genotype/haplotype associated with lower %MMA is denoted first and used as reference group. rs16983411 was excluded from the analysis because there were so few carriers with variant genotypes (n=3). Due to low frequency of carriers of two copies of haplotype3, carriers of one and two copies were merged. ^bp-Values from ANOVA.