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. Author manuscript; available in PMC: 2013 Jul 5.
Published in final edited form as: J Immunol. 2008 May 1;180(9):5784–5788. doi: 10.4049/jimmunol.180.9.5784

Figure 3. EL4 cells can generate CTL with distinct functional avidities.

Figure 3

TgN(TCRP14LCMV) Rag2tm1 cells were stimulated weekly with 10−4M or 10−9M peptide pulsed LPS matured BMDC or EL4 cells. The functional avidity of the resulting CTL lines was determined as in figure 1. Data shown are (A) representative peptide dose-response curves from the lines and (B) the average amount of peptide required to obtain ½ maximal IFNγ production from 4 independently generated lines. *=p<0.05