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. Author manuscript; available in PMC: 2013 Jul 5.
Published in final edited form as: J Immunol. 2008 May 1;180(9):5784–5788. doi: 10.4049/jimmunol.180.9.5784

Figure 4. CTL initially stimulated with mature DC can subsequently modulate their functional avidity following encounter with nonprofessional APC.

Figure 4

Naïve TgN(TCRP14LCMV) Rag2tm1 cells were stimulated with mature BMDC pulsed with high or low amounts of peptide. Post primary stimulation, the CTL were divided and restimulated twice with EL4 cells pulsed with 10−4M or 10−9M peptide. Post-tertiary stimulation, the functional avidity of the CTL lines was determined. The data shown are representative of 4 independently generated panels of lines.