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. 2012 Nov 17;4(1):18–28. doi: 10.18632/oncotarget.725

Figure 4. KDM1 inhibitors reduced proliferation of SLGCs.

Figure 4

(A) Whole cell lysates from various primary GBM cells were subjected to Western blot analysis with KDM1 antibody. β-actin used as an internal control. (B) Primary GBM cells (#101310, 111010, 082209, and 092208) were seeded in 96-well plates and treated with varying concentrations of pargyline or NCL-1 for 72 h and subjected to MTS assay as described in the methods. (C) Primary GBM cells (#111010) were treated with vehicle, pargyline or NCL-1 for 7 days and total RNA was isolated and subjected to RT-qPCR with primers specific for CD133 and nestin. All data presented are the mean ± SEM. *, p< 0.05, t test.