Table 1.
Results of association analyses of DCTN4 and P. aeruginosa phenotypes
| Event | Group | N | # events | HR | 95% CI | pvalue |
|---|---|---|---|---|---|---|
| Age at first Pa+ culture |
no missense any missense |
565 102 |
345 70 |
1.0 1.4 |
-- (1.1,1.8) |
-- 0.01 |
| Age of onset of chronic Pa |
no missense any missense |
565 102 |
93 28 |
1.0 1.9 |
-- (1.2,2.9) |
-- 0.004 |
| Age of onset of chronic Pa |
No missense Het rs11954652 Het rs35772018orhomrs 11954662 |
565 78 22 |
93 20 8 |
1.0 1.7 3.3 |
(1.0, 2.7) (1.5, 6.9) |
0.05 0.002 |
| Age of onset of mucoid Pa |
no missense any missense |
565 102 |
84 16 |
1.0 2.6 |
-- (1.1,5.9) |
-- 0.026 |
| Time from first Pa to mucoid Pa |
no missense any missense |
410 89 |
55 17 |
1.0 3.8 |
-- (1.4, 10.5) |
-- 0.01 |