Fig. 9.

STX antagonizes the cannabinoid-induced decrease in glutamatergic input onto POMC neurons. A, Spontaneous mEPSCs in a cell perfused with 10 nM STX at baseline and following exposure to 1 μM WIN 55,212-2. B, The cumulative probability plot illustrating the interval between contiguous mEPSCs that substantiates the ability of STX to attenuate the inhibitory effect of WIN 55,212-2 on mEPSC frequency. C, Photomicrographs that illustrate the double-labeling of the cell (1, biocytin-streptavidin-AF488 labeling; 2, α-MSH immunofluorescence visualized by AF546; c, composite overlay).