Figure 4.

miR-101 is frequently downregulated in human glioma cell lines and tissues and is associated with a poor prognosis. (a) The expression of miR-101 in normal brain tissue and glioma cell lines. The real-time PCR data indicate that miR-101 is downregulated in glioma cell lines. *P<0.05. (b) The expression of miR-101 in glioma tissues and normal brain tissues. The ISH assay indicates that miR-101 is expressed at high levels in normal brain tissue, whereas the expression is lost in glioma tissues. (c) The correlation between miR-101 expression in the tumor and the OS of glioma patients