Figure 6.

Chloroquine treatment increased hepatic apoptosis following I/R injury. (a) Rats were pre-treated with chloroquine (60 mg/kg) 1 h before warm ischemia, followed by an additional chloroquine injections at 24 h after reperfusion. Caspase-3 and caspase-7 cleavage was observed by western blots in the ischemic lobes at various time points following reperfusion. (b) The gray value of bands was calculated by Image J. Data are shown as mean±S.D. n=6 per group. *P<0.05 compared with vehicle-treated I/R group