Table 2.
Mean (SD) of Baseline and Change Scores in Urine Cortisol and Percent of Days with Moderate-to-Very Severe Stress Levels by Gender and Intervention Group
| Variable | Mean (SD)
|
Mean (SD) change score from baseline
|
P valuea | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | n | 3 Months | n | 6 Months | n | 12 Months | n | ||
| Log10 of cortisol levels (ng/mg creatinine) | |||||||||
| Women | |||||||||
| UC | 1.45 (0.21) | 30 | −0.07 (0.25) | 24 | −0.05 (0.31) | 23 | 0.02 (0.30) | 17 | .175 |
| CSM | 1.42 (0.19) | 60 | 0.05 (0.20) | 46 | −0.00 (0.22) | 45 | 0.01 (0.33) | 42 | |
| Men | |||||||||
| UC | 1.30 (0.07) | 5 | −0.07 (0.17) | 5 | 0.03 (0.15) | 5 | 0.00 (0.13) | 5 | |
| CSM | 1.44 (0.26) | 10 | 0.07 (0.33) | 8 | −0.14 (0.32) | 8 | −0.00 (0.29) | 8 | |
| P valueb | .357 | .353 | .815 | .218 | |||||
|
| |||||||||
| Percent of days with moderate-to-very severe stress levels | |||||||||
| Women | |||||||||
| UC | 26.6 (22.8) | 46 | −1.8 (18.7) | 38 | 3.0 (20.2) | 39 | 2.1 (24.5) | 41 | .277 |
| CSM | 24.2 (22.3) | 94 | −3.6 (20.5) | 88 | −4.3 (18.6) | 83 | −6.0 (17.3) | 83 | |
| Men | |||||||||
| UC | 11.2 (17.3) | 7 | 0.0 (24.6) | 7 | 8.2 (32.0) | 7 | 17.4 (26.2) | 7 | |
| CSM | 17.4 (24.0) | 13 | 14.5 (15.5) | 12 | 4.0 (21.6) | 13 | 5.8 (19.3) | 13 | |
| P valueb | .384 | .043 | .519 | .976 | |||||
UC, usual care; CSM, comprehensive self-management.
a
P values are from mixed model analysis of covariance, using all three follow-up periods to test the interaction effect between gender and the intervention controlling for baseline of the outcome measure and age.
b
P values are from analysis of covariance that test the interaction effect between gender and the intervention at each follow-up time point (3, 6, and 12 months) controlling for baseline of the outcome measure and age.
Table includes all subjects who provided outcome data for at least one of the follow-ups