Table 3.
Correlation of MUC20 expression with clinicopathologic features in CRC patients
| Clinicopathologic features | n |
MUC20 expression n (%) |
χ2 | P | |
|---|---|---|---|---|---|
| Positive | Negative | ||||
| Gender |
|
|
|
0.787 |
0.375 |
| Male |
88 |
56(63.6%) |
32(26.4%) |
|
|
| Female |
62 |
35(56.5%) |
27(43.5%) |
|
|
| Age(years) |
|
|
|
4.261 |
0.039 |
| <60 |
94 |
63(67.0%) |
31(33.0%) |
|
|
| > = 60 |
56 |
28(50.0%) |
28(50.0%) |
|
|
| Tumor size (diameter) |
|
|
1.189 |
0.276 |
|
| <5 |
87 |
56(64.4%) |
31(35.6%) |
|
|
| > = 5 |
63 |
35(55.6%) |
28(44.4%) |
|
|
| Location |
|
|
|
0.224 |
0.636 |
| Colon |
100 |
62(62.0%) |
38(38.0%) |
|
|
| Rectum |
50 |
29(58.0%) |
21(42.0%) |
|
|
| Gross appearance |
|
|
|
0.685 |
0.710 |
| Exophytic |
60 |
34(56.7%) |
26(43.3%) |
|
|
| Ulcerative |
87 |
55(63.2%) |
32(36.8%) |
|
|
| Diffusely infiltrative |
3 |
2(66.7%) |
1(33.3%) |
|
|
| Differentiation |
|
|
|
0.086 |
0.958 |
| High |
7 |
4(57.1%) |
3(42.9%) |
|
|
| Moderate |
111 |
67(60.4%) |
44(39.6%) |
|
|
| Low |
32 |
20(62.5%) |
12(37.5%) |
|
|
| TNM stage |
|
|
|
0.264 |
0.607 |
| II |
80 |
47(58.8%) |
33(41.2%) |
|
|
| III |
70 |
44(62.9%) |
26(37.1%) |
|
|
| Recurrence |
|
|
|
5.849 |
0.016 |
| Yes |
47 |
36(76.6%) |
11(33.4%) |
|
|
| No |
90 |
50(55.6%) |
40(44.4%) |
|
|
| Status |
|
|
|
5.960 |
0.015 |
| Survival |
93 |
52(55.9%) |
41(44.1%) |
|
|
| Death | 41 | 32(78.0%) | 9(22.0%) | ||