Table 4.
Two year death-censored Cox regression analysis
| |
Univariable |
Multivariable model 1 |
Multivariable model 2 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | |
| Delayed graft function |
5.21 |
2.17 to 12.48 |
< 0.001 |
5.04 |
2.05 to 12.42 |
< 0.001 |
5.41 |
2.20 to 13.34 |
< 0.001 |
| IL-2 minus |
4.13 |
1.78 to 9.57 |
0.001 |
4.59 |
1.91 to 11.02 |
0.001 |
3.81 |
1.53 to 9.49 |
0.004 |
| Time on dialysis (per year) |
1.23 |
0.94 to 1.63 |
0.1 |
1.20 |
0.89 to 1.62 |
ns |
1.22 |
0.91 to 1.63 |
ns |
| Recipient gender |
1.72 |
0.65 to 4.58 |
0.3 |
1.26 |
0.46 to 3.43 |
ns |
1.23 |
0.45 to 3.34 |
ns |
| Recipient age |
1.01 |
0.98 to 1.05 |
0.5 |
1.00 |
0.97 to 1.03 |
ns |
1.00 |
0.97 to 1.04 |
ns |
| Steroid-resistant rejection | 3.65 | 1.52 to 8.74 | 0.004 | 2.52 | 1.01 to 6.29 | 0.05 | |||
N = 232; 25 graft loss, no missing variables.
The following variables were tested in the univariable model but not included in the multivariable model: CMV-positive donor, CMV-positive recipient, presence of HLA antibodies, donor age, donor gender, any HLA-A, HLA-B or HLA-DR mismatch, type of calcineurin inhibitor (tacrolimus versus CsA), cold ischemia time and presence of acute rejection episodes 90 or 180 days after transplantation.