Table 5.
Logistic regression analysis: acute rejection episodes during the first 90 days after transplantation
| |
Univariable |
Multivariable |
||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| IL-2 minus |
2.87 |
1.58 to 5.21 |
0.001 |
2.42 |
1.25 to 4.68 |
0.009 |
| Any HLA-DR mismatch |
1.98 |
1.09 to 3.60 |
0.03 |
2.32 |
1.19 to 4.52 |
0.01 |
| Cold ischemia time (per hour) |
0.90 |
0.84 to 0.96 |
0.001 |
0.90 |
0.84 to 0.97 |
0.003 |
| Tacrolimus versus CsA |
0.20 |
0.05 to 0.86 |
0.03 |
0.28 |
0.04 to 1.01 |
ns |
| CMV-positive recipient |
0.46 |
0.24 to 0.90 |
0.02 |
0.62 |
0.30 to 1.30 |
ns |
| Time on dialysis (per year) |
0.84 |
0.66 to 1.06 |
0.14 |
0.82 |
0.63 to 1.06 |
ns |
| Recipient age |
1.00 |
0.98 to 1.02 |
0.88 |
0.98 |
0.95 to 1.01 |
ns |
| Recipient gender (male) | 1.46 | 0.75 to 2.84 | 0.26 | 1.46 | 0.70 to 1.01 | ns |
N=230; 63 rejection episodes, two patients excluded because of missing variables.
The following variables were tested in the univariable model but not included in the multivariable model: CMV-positive donor, presence of HLA antibodies, donor gender, donor age, delayed graft function, any HLA-A or any HLA-B mismatch.