. Author manuscript; available in PMC: 2013 Jul 5.

Published in final edited form as: Am J Physiol Heart Circ Physiol. 2010 Dec 24;300(3):H1032–H1043. doi: 10.1152/ajpheart.00410.2010

Table 1.

Effect of age and catechin treatment on hemodynamic parameters and cholesterol and triglycerides levels in wild-type and atherosclerotic mice

	WT		ATX		6-mo-old ATX 3 CAT
	3 mo old	6 mo old	3 mo old	6 mo old	6-mo-old ATX 3 CAT
Hemodynamic parameters
HR, beats/min	377 ± 19	330 ± 5	371 ± 22	349 ± 11	354 ± 9
SAP, mmHg	94 ± 2	94 ± 3	106 ± 3*	119 ± 3^†	131 ± 5
DAP, mmHg	59 ± 3	63 ± 3	73 ± 2*	82 ± 2^†	90 ± 4
MAP, mmHg	71 ± 3	67 ± 6	84 ± 3*	94 ± 2^†	103 ± 4
Plasma levels
Cholesterol, mmol/l	2.1 ± 0.1	3.1 ± 0.1	16.6 ± 2.0*	20.1 ± 2.2^†	20.1 ± 1.3
LDL, mmol/l	0.5 ± 0.1	1.2 ± 0.1	10.3 ± 1.6*	12.4 ± 1.1^†	12.7 ± 1.0
HDL, mmol/l	1.3 ± 0.1	1.7 ± 0.1	1.7 ± 0.1	1.9 ± 0.1	1.7 ± 0.1
Triglycerides, mmol/l	0.7 ± 0.1	0.7 ± 0.2	6.2 ± 0.5*	7.5 ± 0.8 ^†	8.5 ± 0.8

Values are means ± SE; n = 8–10 mice in each group. WT, wild type; ATX, atherosclerotic; CAT, catechin; HR, heart rate; SAP, systolic arterial pressure; DAP, diastolic arterial pressure; MAP, mean arterial pressure; HDL, high-density lipoprotein; LDL, low-density lipoprotein. P < 0.05 vs. 3-mo-old WT (*) and vs. 6-mo-old WT (^†).