Table 1. Error percentages for 38 studies for the full ordinal scale (mRS 0.6), partially collapsed ordinal scale (mRS 0.3, 4–6) and dichotomization (mRS 0–1, 2–6; mRS 0–2, 3–6; mRS 0–3, 4–6; mRS 0–4, 5–6) and trichotomization (mRS 0–1, 2–4, 5–6; mRS 0–2, 3–4, 5–6) cut-points.

Study [Reference Number]	mRS 0.6	mRS0.3, 4–6	mRS0–1, 2–6	mRS0–2, 3–6	mRS0–3, 4–6	mRS0–4, 5–6	mRS0–1, 2–4, 5–6	mRS0–2, 3–4, 5–6
ABESTT [36]	25.64	23.37	9.41	8.62	6.24	2.27	11.68	10.89
ABESTTII [37]	23.19	20.8	8.04	7.6	6.18	2.39	10.43	9.99
ABESTTIICo [37]	27.26	24.8	9.29	9.77	6.99	2.46	11.75	12.23
ABESTTIIW [37]	31.48	29.73	9.39	14.64	7.68	1.75	11.14	16.39
ARTIS [38]	31.92	30.07	11.07	12.88	8.2	1.85	12.92	14.73
CAIST [39]	26.7	25.22	11.71	8.73	5.84	1.48	13.19	10.21
CASTA-Cereb [40]	30.4	27.44	9.39	11.49	8.24	2.96	12.35	14.45
Camerlingo [41]	24.71	18.09	5.54	7.26	6.2	6.62	12.16	13.88
Cereb-rt-pa [42]	23.45	21.94	9.73	7.3	6.07	1.51	11.24	8.81
DECIMAL [3]	7.76	5.93	0	1.68	4.25	1.83	1.83	3.51
DESTINY [4]	18.98	15.19	0	8.17	7.02	3.79	3.79	11.96
DP-b99 [43]	25.84	20.41	4.87	7.75	9.07	5.43	10.3	13.18
DP-b99-MACSI [44]	27.15	23.23	7.67	8.9	7.52	3.92	11.59	12.82
ECASSII [45]	25.4	22.53	6.48	8.59	8.2	2.87	9.35	11.46
ECASSIII [46]	22.09	19.37	8.93	6.56	4.96	2.72	11.65	9.28
EPITHET [47]	27.83	23.9	7.85	9.1	8.16	3.93	11.78	13.03
EPO [48]	26.13	20.76	7.08	7.1	7.42	5.37	12.45	12.47
Edaravone [49]	29.37	26.69	13.2	9.22	6.16	2.68	15.88	11.9
Enlimomab [50]	24.61	21.55	7.02	8.75	6.91	3.06	10.08	11.81
FIST [51]	24.14	20.39	5.15	9.33	7.03	3.75	8.9	13.08
GAIN [52]	26.19	21.55	5.61	8.02	8.93	4.64	10.25	12.66
HAMLET [5]	16.99	15.62	1.79	7.43	7.18	1.37	3.16	8.8
ICTUS [53]	25.14	21.24	4.85	8.53	8.93	3.9	8.75	12.43
IMS-III [54]	25.54	22.49	7.35	9.26	6.9	3.05	10.4	12.31
INSULINFARCT [55]	29.59	27.27	8.66	11.46	9.11	2.32	10.98	13.78
IST-3 [22]	23.05	18.38	6.31	7.56	5.52	4.67	10.98	12.23
MELT [56]	32.31	25.52	7.45	10.83	8.58	6.79	14.24	17.62
MR-RESCUE-Pen [57]	32.33	26.17	4.45	11.1	11.22	6.16	10.61	17.26
MR-RES-Non-Pen [57]	25.97	17.26	1.89	6.44	9.28	8.71	10.6	15.15
Minocycline [58]	44.37	43.99	6.99	24.82	14.12	0.38	7.37	25.2
NEST-1 [59]	27.22	22.53	7.2	8.53	7.43	4.69	11.89	13.22
NEST-2 [60]	29.17	25.13	5.69	10.94	9.84	4.04	9.73	14.98
NINDS [61]	23.96	20.57	6.19	7.88	7.45	3.39	9.58	11.27
PROACTII [62]	24.09	20.31	2.85	8.89	9.16	3.78	6.63	12.67
SAINTI [20]	25.08	21.71	7.6	7.13	7.96	3.37	10.97	10.5
SAINTII [21]	26.24	22.5	7.3	9.02	7.26	3.74	11.04	12.76
Synthesis [63]	25.16	22.32	5.02	7.32	10.25	2.84	7.86	10.16
Synthesis Exp [64]	26.51	22.88	7.12	8.18	8.35	3.63	10.75	11.81