Table 4. Aspects of study level publication bias.
Study | Definition of published article employed by eligible studies | Time since protocol approved | % Not submitted1 (95% CI) | % Submitted but not accepted2 (95% CI) | % Studies not published that were not submitted (95% CI) |
Easterbrook, 1991 [24] | Acceptance by a journal (published or in press), but not book chapters or published meeting abstracts or proceedings. | 3 years | 9 (6, 12) | 6 (3, 9) | 63 (49, 77) |
Dickersin, 1992 [23] | Reported in one or more journal articles, monographs, books, or chapters in books, were available from medical libraries or were in documents available from a published archive, e.g., the National Technical Information service | 8 years | 23 (19, 27) | 1.5 (0, 3) | 95 (91, 99) |
Dickersin, 1993 [3] | Abstracts, journal articles, book chapters, proceedings, letter to the editor, or other material. | 9 years | 7 (3, 11) | 0 | 100 |
Stern, 19973 [4] | As an article in a peer reviewed journal | 4 plus years | 33 (28, 38) | 13 (8,17) | 80 (73, 87) |
Cooper, 1997 [19] | NI | NI | NI | ||
Wormald, 1997 [30] | NI | 2 to 34 years | 21 (8,34) | 0 | 100 |
Ioannidis, 1998 [5] | Peer-reviewed journal articles | 12% completed less than 1 year ago, 20% completed over 1 year ago. | 32 (21, 43) | 20 (8, 32) | 70 (54, 86) |
Pich, 2003 [27] | Peer reviewed journal articles | 3 years | * | ||
Cronin, 2004 [20] | NI | 1 to 5 years | * | ||
Decullier, 20053 [7] | Published as a scientific paper. Grey literature – published in other formats than scientific papers, that is generally not accessible through libraries (internal reports, theses, abstracts, posters) | 6 years (2% not ready) | 58 (54,62) | 2 (0, 4) | 99 (98, 100) |
Decullier, 20063 [22] | Published as a scientific paper | 6 years | 47 (37,57) | 2 (0, 6) | 98 (95, 100) |
Hahn, 2002 [26] | Published article or a written study report | 5 years | * | ||
Chan, 2004a3 [18] | Journal article | 4 years | 31 (22,40) | 1 (0, 3) | 97 (91, 100) |
Chan, 2004b3 [17] | Journal article | 8 years | 56 (50, 62) | 2 (0, 5) | 99 (97, 100) |
Ghersi, 2006 [25] | NI | NI | NI | ||
Von Elm, 2008 [29] | Journal article | 8 years | * | ||
Turer 2007 [28] | Peer reviewed journal articles | 7 years | 26 (20,33)4 | * | * |
De jong 2010 [21] | An original article containing study results, indexed in MEDLINE, EMBASE, PsychINFO, or the Cochrane Library | 6 months to 9 years | NI | ||
Blumle 2008 [31] | Articles published in scientific journals that provide adequate information on at least the objectives of the study as well as on its methods and results | 7 years | * | ||
Hall 2007 [32] | Peer reviewed journal | 10–11 years | NI |
Denominator is the total number of studies with known publication status in the cohort i.e. published plus unpublished plus in preparation plus in press.
Denominator is the number submitted.
Denominator includes ongoing studies.
This is the number never presented and we have assumed not submitted.
Question not asked. NI No information available.