Figure 7. Inhibition of endogenous PTEN activity had no effect on high KCl (60 mM) induced cerebral arterial constriction.

The high KCl (60 mM) induced constriction of pressurized (40 mm Hg) cerebral arterial segments was not influenced by pretreatment with either of the PTEN inhibitors bpV(phen) (10 µM or 30 µM) (A) or bpV(pic) (10 µM or 30 µM) (B). *denotes significant difference from control at p<0.05; n = 4–5 independent studies.