Table 3.
Adjusted mean hemostatic factor levels by statin potency, MESA, 2000–2002
| Statin Potency | p-trend | ||||
|---|---|---|---|---|---|
| Low | Medium | High | |||
| N | 232 | 579 | 190 | ||
| D-Dimer*, ug/ml | Model 1† | 0.26 | 0.23 | 0.25 | 0.38 |
| Model 2 | 0.26 | 0.22 | 0.25 | 0.40 | |
| Fibrinogen, mg/dL | Model 1 | 366 | 357 | 363 | 0.56 |
| Model 2 | 365 | 356 | 363 | 0.60 | |
| Factor VIII, % | Model 1 | 164 | 170 | 166 | 0.61 |
| Model 2 | 163 | 169 | 163 | 0.88 | |
| Homocysteine*, umol/L | Model 1 | 9.20 | 9.05 | 9.10 | 0.66 |
| Model 2 | 9.28 | 9.08 | 9.14 | 0.56 | |
| CRP*, mg/L | Model 1 | 2.06 | 1.60 | 1.65 | 0.02 |
| Model 2 | 2.04 | 1.62 | 1.63 | 0.02 | |
| N (MESA 1,000) | 23 | 74 | 20 | ||
| vWF, % | Model 1 | 161 | 139 | 132 | 0.12 |
| Model 2 | 160 | 140 | 140 | 0.27 | |
| PAI-1*, ng/ml | Model 1 | 36.8 | 19.0 | 23.9 | 0.10 |
| Model 2 | 36.8 | 19.4 | 25.4 | 0.12 | |
*
Geometric means reported
†
Model covariates as in Table 2.