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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Ophthalmology. 2013 Apr 16;120(7):1324–1336. doi: 10.1016/j.ophtha.2012.12.044

Figure 5. High frequency of abnormalities of the tear film, tear production, and ocular surface damage in Xeroderma pigmentosum (XP)-affected patient eyes.

Figure 5

A) Tear film breakup times (TBUTs) ≤5 seconds are considered abnormal. No patients had TBUT measured over multiple visits. B) Baseline aqueous tear production measured by Schirmer test II. Schirmer test II values > 10 mm/5 minutes (min) indicate normal baseline tear production, values from 6 mm/5 min to 10 mm/5 min is considered borderline aqueous tear deficiency, and ≤ 5 mm/5 min confirms an aqueous-deficient dry eye categorization.32 C) Quantification of ocular surface damage in XP-affected patients via epithelial surface staining with fluorescein. The state of the ocular surface was assessed in each patient able to undergo the procedure and graded according to the Oxford Scale. Because not all patients were able to cooperate with this testing, data are available on only a subset of patients.