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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Cancer Res. 2013 May 23;73(13):3938–3950. doi: 10.1158/0008-5472.CAN-13-0002

Figure 2. Expression of mTNFα does not affect tumor proliferation or vascularity in vivo.

Figure 2

(A) Representative sections of LLC tumors transduced with control, IL2spTNFα and mTNFα constructs were analyzed by immunohistochemistry for PECAM-1 or Ki-67 staining to define vascularity or proliferation, respectively. (B and C) Percentage of PECAM-1-positive (B) or Ki-67-positive area (C) in control, IL2spTNFα and mTNFα in LLC tumors was quantitated. There was no significant difference between the cohorts for either PECAM-1-positive or Ki-67-positive cells (P>0.05), 1-way ANOVA with Tukey’s post-test.