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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Cancer Res. 2013 May 23;73(13):3938–3950. doi: 10.1158/0008-5472.CAN-13-0002

Figure 7. Relative expression pattern of TNFα/TACE correlates with survival probability in lung cancer patients.

Figure 7

(A) Analysis of TNFα expression from 40 human non-small cell lung carcinoma (NSCLC) tissue array. Graph displays the distribution of both degree and localization of TNFα staining 40 NSCLC patient samples. (B) Expression pattern of sTNFα and mTNFα in human NSCLC cell lines measured by ELISA and immunoblotting methods, respectively. A significant variation was observed in the ratio of mTNFα to sTNFα expressed by each cell line. (C) Association between TNFα and TACE co-expression pattern and survival probability in patients with NSCLC. Analysis of the publicly available data from the Shedden cohort (17) was used to correlate TNFα/TACE expression pattern with survival probability (n=442, log rank P=0.035).