Table 1.
Participant characteristics
| Gadofosveset trisodium (exam 1) |
Gadobenate Dimeglumine (exam 2) |
p value* |
|
|---|---|---|---|
| Demographics | |||
| Age | 27.9±6.7 | 27.9±6.7 | N/A |
| Male | 8 (36) | 8 (36) | N/A |
| Height (cm) | 169.5±8.1 | 169.5±8.1 | N/A |
| Weight (kg) | 65.7±9.5 | 65.1±10.0 | 0.13 |
| Body mass index (Kg/m2) | 22.8±2.0 | 22.6±2.1 | 0.09 |
| Hematocrit (%) | 42.6±3.5 | 42.1±3.7 | 0.45 |
| Creatine (mg/dL) | 0.8±0.2 | 0.8±0.1 | 0.63 |
| eGFR (mL/min/1.73 m2) | 97.7±16.5 | 97.7±16.6 | 1.00 |
| Heart rate (bpm) | 63.1±10.4 | 69.7±14.4 | 0.03 |
| Systolic blood pressure (mmHg) | 121.6±12.5 | 125.2±12.8 | 0.18 |
| Diastolic blood pressure (mmHg) | 72.7±6.7 | 72.5±7.8 | 0.90 |
| LV Systolic function by CMRI | |||
| EDV (ml) | 131.4±29.6 | 132.8±24.5 | 0.50 |
| ESV (ml) | 45.6±13.6 | 45.2±13.1 | 0.73 |
| EF (%) | 65.4±5.0 | 66.4±5.7 | 0.19 |
| Mass (g) | 126.3±32.3 | 124.7±31.2 | 0.27 |
| Contrast administration | |||
| Dose (mL) | 7.9±1.1 | 13.1±2.2 | <0.001 |
| LGE by CMRI | |||
| Negative | 0 (0) | 0 (0) | N/A |
*
Note: p value, comparison between exam 1 vs exam 2. Mean and standard deviations or number and percentages as appropriate. LV, left ventricular; EDV, end-diastolic volume; ESV, endsystolic volume; EF, ejection fraction; LGE, late gadolinium enhancement; and N/A, not applicable.