Table II.
Comparison of the laboratory examination of both groups.
| PTU-associated small-vessel vasculitis (n=10) | Primary AAV (n=18) | Statistical data | P-value | |
|---|---|---|---|---|
| Indirect immunofluorescence of ANCA | ||||
| Number of patients with p-ANCA | 10 (100.0%) | 10 (55.6%) | - | 0.02 |
| Number of patients with c-ANCA | 0 (00.0%) | 8 (44.4%) | - | 0.02 |
| ELISA of ANCA | ||||
| Number of patients with MPO-ANCA only | 8 (80.0%) | 11 (61.1%) | ||
| Number of patients with PR3-ANCA only | 1 (10.0%) | 7 (38.9%) | χ2=0.63 | 0.42 |
| Number of patients with double positive | 1 (10.0%) | 1 (10.0%) | 0 (0.0%) | |
| Number of patients with gross hematuria | 1 (10.0%) | 10 (55.6%) | - | 0.04 |
| 24 h proteinuria content (mg/24 h) | 578.5±119.7 | 1541.7±334.7 | t=−11.0 | 0.00 |
| Creatinine (μmol/l) | 159.9±50.9 | 567.6±112.1 | t=−13.1 | 0.00 |
PTU, propylthiouracil; AAV, ANCA-associated small-vessel vasculitis; ANCA, anti-neutrophil cytoplasmic antibody; p-ANCA, perinuclear anti-neutrophil cytoplasmic antibody; c-ANCA, cytoplasmic anti-neutrophil cytoplasmic antibody; ELISA, enzyme-linked immunosorbent assay; MPO, myeloperoxidase; PR3, proteinase 3.