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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Dermatol Clin. 2013 Jun 2;31(3):405–425. doi: 10.1016/j.det.2013.04.001

Table 2.

Proposed criteria for CRMO and non bacterial osteitis56

Major diagnostic criteria Minor diagnostic criteria

  1. Radiologically proven osteolytic/-sclerotic bone lesion

  2. Multifocal bone lesions

  3. PPP or psoriasis

  4. Sterile bone biopsy with signs of inflammation and/or fibrosis, sclerosis

  1. Normal blood count and good general state of health

  2. CRP and ESR mildly to moderately elevated

  3. Observation time longer than 6 mo

  4. Hyperostosis

  5. Associated with other autoimmune diseases apart from PPP or psoriasis

  6. Grade I or II relatives with autoimmune or autoinflammatory disease, or with non-bacterial osteitis

Two major criteria or one major and three minor criteria is sufficient for diagnosis of CRMO.