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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Dermatol Clin. 2013 Jun 2;31(3):405–425. doi: 10.1016/j.det.2013.04.001

Table 3.

Diagnostic criteria for generalized pustular psoriasis87

All 5 criteria must be met for diagnosis.
  1. Systemic symptoms such as fever and general malaise are present

  2. Multiple, isolated non-infectious pustules are present in the flushed skin all over the body or over a wide area

  3. Kogoj’s spongiform pustules are histopathologically confirmed

  4. Some of the following laboratory test results are obtained during the clinical course
    • Leukocytosis and shift to the left
    • Precipitated ESR, positive C-reactive protein and high anti-streptolysin O antibody levels
    • Increases in IgG or IgA
    • Hypoproteinemia, hypocalcemia, etc
  5. Recurrence of the above-listed clinical and histological findings