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. Author manuscript; available in PMC: 2013 Jul 6.
Published in final edited form as: Physiol Behav. 2010 Oct 14;102(1):96–104. doi: 10.1016/j.physbeh.2010.09.025

Figure 2. Locomotor response of intact and gonadectomized male rats to different doses of cocaine.

Figure 2

Total horizontal (A) and stereotyped (B) activity of INT and GDX male rats is presented as the mean sum ± SEM of the first 30 minutes after a single injection of saline (0.9%) or cocaine (10, 15 or 30mg/kg); N: Saline: INT = 8, GDX = 8; 10mg/kg: INT = 11, GDX = 10; 15mg/kg: INT = 30 (STRCNT) 31(HACTV), GDX = 29; 30mg/kg: INT = 9, GDX = 9. Cocaine increased locomotor activity of all animals compared to their saline counterpart. Gonadectomy enhanced the locomotor response to 15 and 30mg/kg of cocaine when compared to intact males. * p<0.05 compared to LMA of INT animals with the same dose of cocaine.