Table 1.
Diagnostic Accuracy of Xpert (On Stool and Induced Sputum) and Smear Microscopy (On Induced Sputum), When Using Liquid Culture of 2 Induced Sputum Samples as a Reference Standard
| Diagnostic Test | Sensitivity, Test Positive/Total Culture Positive, % (95% CI) | Specificity, Test Negative/Total Culture Negative, % (95%CI) |
|---|---|---|
| Stool Xperta | ||
| All | 8/17, 47.1% (26.2–69.0) | 97/98, 99.0% (94.4–99.8) |
| HIV infected | 4/5, 80.0% (37.6–96.4) | 12/12, 100% (75.8–100) |
| HIV uninfected | 4/12, 33.3% (13.8–61.0) | 85/86, 98.8% (93.7–99.8) |
| Induced sputum Xpert | ||
| All | 11/17, 64.7% (41.3–86.7) | 95/98, 96.9% (91.4–99.0) |
| HIV infected | 3/5, 60.0% (23.1–88.2) | 11/12, 91.7% (64.6–98.5) |
| HIV uninfected | 8/12, 66.7% (39.1–86.2) | 85/86, 98.8% (93.7–99.8) |
| Induced Sputum Smear | ||
| All | 4/17, 23.5% (9.6–47.3) | 98/98, 100% (96.2–100) |
| HIV infected | 3/5, 60.0% (23.1–88.2) | 12/12, 100% (75.8–100) |
| HIV uninfected | 1/12, 8.3% (1.5–35.4) | 86/86, 100% (95.7–100) |
Abbreviations: CI, confidence interval; HIV, human immunodeficiency virus.
a Two Xpert tests performed on a single stool sample.