Table 2.
Expression levels of the mucin core proteins in the adenoma carcinoma sequence
|
Histology |
MUC2 |
MUC5AC |
||||||
| No. of patient | Adenoma | Carcinoma | Adenoma | Carcinoma | P value1 | Adenoma | Carcinoma | P value1 |
| 208 | TV | WMDA | 4 | 3 | ND | 4 | 1 | ND |
| 225 | T | WMDA | 4 | 4 | 3 | 2 | ||
| 237 | TV | WMDA | 4 | 4 | 2 | 4 | ||
| 243 | TV | WMDA | 4 | 4 | 4 | 4 | ||
| 84 | TV | PDA | 4 | 2 | 0.016 | 4 | 0 | 0.042 |
| 86 | TV | PDA | 4 | 0 | 1 | 0 | ||
| 87 | TV | PDA | 4 | 0 | 0 | 0 | ||
| 102 | TV | PDA | 4 | 0 | 4 | 0 | ||
| 116 | T | PDA | 2 | 0 | 2 | 0 | ||
| 138 | T | PDA | 4 | 0 | 3 | 0 | ||
| 148 | T | PDA | 3 | 0 | 0 | 0 | ||
| 15 | TV | MUA | 4 | 4 | 0.063 | 3 | 0 | 0.016 |
| 36 | TV | MUA | 4 | 4 | 3 | 3 | ||
| 37 | TV | MUA | 4 | 4 | 0 | 0 | ||
| 51 | TV | MUA | 4 | 4 | 3 | 3 | ||
| 131 | T | MUA | 4 | 2 | 3 | 1 | ||
| 148 | TV | MUA | 4 | 2 | 4 | 0 | ||
| 151 | TV | MUA | 4 | 3 | 3 | 1 | ||
| 155 | TV | MUA | 4 | 4 | 4 | 2 | ||
| 175 | TV | MUA | 4 | 4 | 4 | 2 | ||
| 191 | TV | MUA | 4 | 3 | 3 | 0 | ||
1
Wilcoxon signed-rank test. MUC: Mucin; T: Tubular adenoma; TV: Tubulovillous adenoma; WMDA: Well-to-moderately differentiated adenocarcinoma; PDA: Poorly differentiated adenocarcinoma; MUA: Mucinous adenocarcinoma; ND: Not determined.