Table 4.

Ixabepilone concentrations (ng/ml) by timepoint following first dose

Time (h)	30 mg×3		40 mg×3		50 mg×3
	Mean	0%CV	Mean	0%CV	Mean	0%CV
0	NC	00NC	NC	00NC	NC	00NC
0.5	2.77	00NC	11.46	00NC	7.86	00NC
1	9.31	00NC	19.93	106.86	41.82	125.4
2	29.67	199.38	73.57	110.45	104.91	150.51
3	52.75	104.05	56.82	158.61	124.51	153.14
4	24.18	156.31	30.23	172.12	52.16	159.89
5	16.64	158.09	22.24	183.73	36.54	157.84
6	12.84	160.79	17.75	189.73	32.08	162.8
8	11.19	134.62	32.5	102.55	104.54	117.48
12	26.76	131.55	24.84	154.32	49.41	153.78
12.5	24.24	125.04	22.58	156.1	78.35	131.39
13	17.63	116.13	25.94	116.42	103.42	160.96
14	19.60	127.42	52.17	199.15	59.02	125.4
15	18.52	124.55	39.52	175.4	86.3	155.37
16	27.37	185.28	43.62	186.26	93.53	154.94
17	76.63	103.25	37.31	189.18	116.04	169.01
18	38.32	171.54	41.13	110.4	94.27	151.59
20	24.71	169.61	43.04	189.19	89.71	187.4
48	11.77	135.33	13.6	130.63	24.41	162.82
72	7.20	128.48	10.49	120.83	14.81	164.98
168	3.12	00NC	7.8	100.52	6.28	194.02