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Alignment of the VFT sequence of VKR proteins using the CLUSTAL W algorithm. Lobe I and Lobe II (indicated by the upper black line) and the three linkers (L1, L2, L3) constitute the structure of VFT domains. Residues highlighted in red are highly conserved in all or most VKR sequences, and residues highlighted in green correspond to the consensus amino-acid binding motif of VFT domains [24].
