. Author manuscript; available in PMC: 2013 Sep 1.

Published in final edited form as: Circ Cardiovasc Imaging. 2012 Jun 28;5(5):596–603. doi: 10.1161/CIRCIMAGING.112.973321

Table 4.

Sensitivity, Specificity, PPV, and NPV of the Predictors of Cardiotoxicity

Predictors (Measured At the Completion of Anthracyclines)	Sensitivity	Specificity	PPV	NPV
Long strain <19%	17/23 (74%) (0.51–0.90)	40/55 (73%) (0.59–0.84)	17/32 (53%)	40/46 (87%)
usTnI >30 pg/mL	11/23 (48%) (0.27–0.69)	40/55 (73%) (0.59–0.84)	11/26 (44%)	40/52 (77%)
Long strain <19% and usTnI>30 pg/mL	8/23 (35%) (0.16–0.57)	51/55 (93%) (0.82–0.98)	8/12 (67%)	51/66 (77%)
Long strain <19% or usTnI>30 pg/mL	20/23 (87%) (0.66–0.97)	29/55 (53%) (0.39–0.66)	20/46 (43%)	29/32 (91%)

PPV indicates positive predictive value; NPV, negative predictive value; and usTnI, ultrasensitive troponin I.

Long strain is peak systolic longitudinal myocardial strain.

The 95% exact CIs are provided in brackets.